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Klin Monbl Augenheilkd 2017; 234(04): 571-574
DOI: 10.1055/s-0042-122442
Der interessante Fall
Georg Thieme Verlag KG Stuttgart · New York

Severe Idiopathic Posterior Scleritis in a Patient with HIV

Schwere Idiopathic-posterior-Scleritis in einem HIV-Patienten
M. Sherif
1   Hôpital Ophtalmique Jules-Gonin, Fondation Asile des Aveugle, Université de Lausanne, Switzerland
,
L. Leon
2   Hôpital de la Providence, Neuchâtel, Switzerland
,
O. Clerc
3   Hôpital de Pourtales, Neuchâtel, Switzerland
,
Y. Guex-Crosier
1   Hôpital Ophtalmique Jules-Gonin, Fondation Asile des Aveugle, Université de Lausanne, Switzerland
› Author Affiliations
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Publication History

Publication Date:
01 February 2017 (online)

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Introduction

Scleritis is a serious inflammatory disease which is often associated with systemic autoimmune diseases such as granulomatosis with polyangiitis or rheumatoid arthritis [1]. Scleritis often is the first symptom to present in connective tissue diseases [1], [2]. In HIV positive patients, infections such as syphilis [3], tuberculosis [4] or toxoplasmosis are considered as the classical causes of scleritis.

To the best of our knowledge this is the first case report of severe posterior scleritis in a HIV positive patients, whom presented with none of the classical risk factors (i.e. syphilis, tuberculosis and toxoplasmosis were negative). Moreover, this case the severe scleral inflammation was also associated with superior serous retinal detachment which to date has rarely been reported [5], [6], [7].

 

  • References

  • 1 Akpek EK, Thorne JE, Quazi FA. et al. Evaluation of patients with scleritis for systemic disease. Ophthalmology 2004; 111: 501-506
    CrossrefPubMedGoogle Scholar
  • 2 Okhravi N, Odufuwa B, McCluskey P. et al. Scleritis. Surv Ophthalmol 2005; 50: 351-363
    CrossrefPubMedGoogle Scholar
  • 3 Moloney G, Branley M, Kotsiou G. et al. Syphilis presenting as scleritis in an HIV-positive man undergoing immune reconstitution. Clin Exp Ophthalmol 2004; 32: 526-528
    CrossrefPubMedGoogle Scholar
  • 4 Miranda AF, Cardoso J, Marques N. et al. Isolated posterior scleritis associated with tuberculosis. Arq Bras Oftalmol 2016; 79: 111-112
    PubMedGoogle Scholar
  • 5 Kellar JZ, Taylor BT. Posterior scleritis with inflammatory retinal detachment. West J Emerg Med 2015; 16: 1175-1176
    CrossrefPubMedGoogle Scholar
  • 6 Riono WP, Hidayat AA, Rao NA. Scleritis: a clinicopathologic study of 55 cases. Ophthalmology 1999; 106: 1328-1333
    CrossrefPubMedGoogle Scholar
  • 7 McCluskey PJ, Watson PG, Lightman S. et al. Posterior scleritis: clinical features, systemic associations, and outcome in a large series of patients. Ophthalmology 1999; 106: 2380-2386
    CrossrefPubMedGoogle Scholar
  • 8 Walker NF, Scriven J, Meintjes G. et al. Immune reconstitution inflammatory syndrome in HIV-infected patients. HIV AIDS (Auckl) 2015; 7: 49-64
    PubMedGoogle Scholar
  • 9 Tappeiner C, Walscheid K, Heiligenhaus A. Diagnosis and treatment of episcleritis and scleritis. Ophthalmologe 2016; 113: 797-810
    CrossrefPubMedGoogle Scholar