Cyclical Spontaneous Resorption of Serous Macular Detachment Associated with Optic Disc Coloboma

Background

Optic nerve coloboma is a rare congenital anomaly of the optic disc, which is the result of incomplete closure of the embryonic fissure. This condition can either be an isolated finding, or it can be found in association with multiple congenital anomalies [1]. It has been associated with serous macular detachment, although the exact pathogenesis of this complication is not completely understood [2]. Linear resolution of the serous macular detachment has been described previously [3]. In contrast, we describe here, the case of a cyclical resorption of the submacular fluid.

• References

• 1 Hsu CL, Layton CJ. Familial disorders of the optic disc: presentation of a mother and daughter and review of the literature. Case Rep Ophthalmol 2015; 6: 251-259
• 2 Lin CC, Tso MO, Vygantas CM. Coloboma of optic nerve associated with serous maculopathy. A clinicopathologic correlative study. Arch Ophthalmol 1984; 102: 1651-1654
• 3 Romero R, Castaño A, García J et al. Spontaneous resolution of macular detachment associated with optic disc coloboma. Arch Soc Esp Oftalmol 2013; 88: 279-282
• 4 Chang S, Gregory-Roberts E, Chen R. Retinal detachment associated with optic disc colobomas and morning glory syndrome. Eye (Lond) 2012; 26: 494-500
• 5 Meirelles RL, Aggio FB, Costa RA et al. STRATUS optical coherence tomography in unilateral colobomatous excavation of the optic disc and secondary retinoschisis. Graefes Arch Clin Exp Ophthalmol 2005; 243: 76-81
• 6 Bartz-Schmidt KU, Heimann K. Pathogenesis of retinal detachment associated with morning glory disc. Int Ophthalmol 1995; 19: 35-38
• 7 Perkins SL, Han DP, Gonder JR et al. Dynamic atypical optic nerve coloboma associated with transient macular detachment. Trans Am Ophthalmol Soc 2005; 103: 116-123
• 8 Postel EA, Pulido JS, McNamara JA et al. The etiology and treatment of macular detachment associated with optic nerve pits and related anomalies. Trans Am Ophthalmol Soc 1998; 96: 73-88