Planta Med 2016; 82(08): 734-741
DOI: 10.1055/s-0042-102660
Natural Product Chemistry and Analytical Studies
Original Papers
Georg Thieme Verlag KG Stuttgart · New York

Chemical Constituents from Campylotropis hirtella

Yang-Guo Xie*
1   School of Pharmacy, Shanghai Jiao Tong University, Shanghai, P. R. China
,
Tao Li*
4   Key Laboratory of Animal Parasitology, Ministry of Agriculture, Shanghai Veterinary Research Institute, Shanghai, P. R. China
,
Guo-Wei Wang
3   College of Pharmaceutical Sciences and Chinese Medicine, Southwest University, Chongqing, P. R. China
,
Jie Ren
1   School of Pharmacy, Shanghai Jiao Tong University, Shanghai, P. R. China
,
Xing Wang
1   School of Pharmacy, Shanghai Jiao Tong University, Shanghai, P. R. China
,
Ya-Ping Pan
1   School of Pharmacy, Shanghai Jiao Tong University, Shanghai, P. R. China
,
Hui-Liang Li
2   Department of Phytochemistry, Second Military Medical University, Shanghai, P. R. China
,
Shi-Kai Yan
1   School of Pharmacy, Shanghai Jiao Tong University, Shanghai, P. R. China
,
Hui-Zi Jin
1   School of Pharmacy, Shanghai Jiao Tong University, Shanghai, P. R. China
,
Wei-Dong Zhang
1   School of Pharmacy, Shanghai Jiao Tong University, Shanghai, P. R. China
2   Department of Phytochemistry, Second Military Medical University, Shanghai, P. R. China
› Author Affiliations
Further Information

Publication History

received 07 October 2015
revised 03 January 2016

accepted 29 January 2016

Publication Date:
24 May 2016 (online)

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Abstract

A phytochemical investigation on the roots of Campylotropis hirtella afforded nine new isoflavones (39, 12, 15), two new isoflavans (10 and 11), one new coumestan (1), and three new prenylated benzoic acid derivatives (2, 13, 14), together with twenty-four known compounds. Their structures were established by spectroscopic analysis and circular dichroism data. The isolated compounds were also evaluated for their antibacterial activities against Enterococcus faecalis, Salmonella gallinarum, Streptococcus suis, Streptococcus agalactiae, Aeromonas hydrophila, Pseudomonas aeruginosa, Bacillus subtilis, Riemerella anatipestifer, and Vibrio alginolyticus.

* Co-first authors who contributed equally to this work.


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