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Planta Med 2016; 82(08): 723-728
DOI: 10.1055/s-0042-100915
DOI: 10.1055/s-0042-100915
Natural Product Chemistry and Analytical Studies
Original Papers
Polycyclic Spiro Lignans and Biphenyl Tetrahydrofuranone Lignans from Gymnotheca involucrata
Further Information
Publication History
received 13 October 2015
revised 01 December 2015
accepted 22 December 2015
Publication Date:
12 February 2016 (online)
Abstract
Four rare polycyclic spiro lignans (1–4) and four new biphenyl tetrahydrofuranone lignans (5–8) were isolated from the whole plant of Gymnotheca involucrata. The structures of the new compounds were elucidated on the basis of detailed spectroscopic analysis and the absolute configuration of 1 was confirmed by single crystal X-ray diffraction. Bioassay results showed that compounds 2 and 6 exhibited weak antifungal activity against Uromyces viciae-fabae at 100 ppm in leaf-disc assays, while compound 3 demonstrated moderate insecticidal activity against Diabrotica balteata at 500 ppm in an artificial diet assay.
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