Magnifying Endoscopy For Diagnosis of Gastric Intestinal Metaplasia: Can we see the “Light Blue Crest” Sign with I-Scan Optical Enhancement?

Aims The aim of this study was to evaluate the diagnostic efficacy of “light blue crest” (LBC) sign in diagnosis of gastric intestinal metaplasia with magnifying i-scan optical enhancement endoscopy (PENTAX Medical, Japan).

Methods 86 gastric lesions in 46 patients (mean age 52.1 years, SD=10.2, 54 % male, 46 % female) were inspected with magnifying endoscopy and i-scan optical enhancement (EPK-i7010, endoscope EG-2990Zi, PENTAX Medical). LBC was defined as a fine, blue-white line on the crests of the epithelial surface/gyri under magnifying observation with image enhancement endoscopy. Forceps biopsy was performed for a histological evaluation of lesions.

Results From 86 gastric lesions GIM was confirmed in 31 cases (complete GIM – in 14 cases, incomplete GIM – in 8 cases, mixed GIM – in 9 cases). LBC sign was observed in 22 cases. All lesions with detected LBC confirmed as GIM. Sensitivity, specificity, accuracy, positive predictive value, negative predictive value for LBC sign in diagnosis of GIM were 0.71, 1.00, 0.90, 1.00, 0.86, respectively.

Conclusions Magnifying endoscopy with i-scan optical enhancement technology provides accurate diagnosis of GIM by using LBC sign. Further studies are needed to evaluate the efficacy of different previously described endoscopic features of IM using new optical technologies.

Citation: Kashin S, Kuvaev R, Kraynova E et al. OP50 MAGNIFYING ENDOSCOPY FOR DIAGNOSIS OF GASTRIC INTESTINAL METAPLASIA: CAN WE SEE THE “LIGHT BLUE CREST” SIGN WITH I-SCAN OPTICAL ENHANCEMENT?. Endoscopy 2021; 53: S23.

Publication History

Article published online:
19 March 2021