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Klin Monbl Augenheilkd 2016; 233(04): 524-526
DOI: 10.1055/s-0041-111824
Der interessante Fall
Georg Thieme Verlag KG Stuttgart · New York

Can Low Dose Radiation Therapy (2 × 2 Gy) be Used in Primary Bilateral Conjunctival Follicular Lymphoma?

Kommt eine niedrig dosierte Radiotherapie (2 × 2 Gy) bei primären bilateralen follikulären Bindehaut-Lymphom infrage?
S. Cotting-Bodmer
1   Hôpital ophtalmique Jules-Gonin, FAA, Département dʼophtalmologie, Université de Lausanne, Switzerland (Chairman: Prof. Dr. Francine Behar-Cohen)
,
A. Moulin
1   Hôpital ophtalmique Jules-Gonin, FAA, Département dʼophtalmologie, Université de Lausanne, Switzerland (Chairman: Prof. Dr. Francine Behar-Cohen)
,
C. P. Herbort Jr.
1   Hôpital ophtalmique Jules-Gonin, FAA, Département dʼophtalmologie, Université de Lausanne, Switzerland (Chairman: Prof. Dr. Francine Behar-Cohen)
2   Centre dʼophtalmologie spécialisé, Lausanne, Switzerland
,
N. Ketterer
3   Institut de radio-oncologie, Clinique Bois-Cerf, Lausanne, Switzerland
,
M. Betz
3   Institut de radio-oncologie, Clinique Bois-Cerf, Lausanne, Switzerland
,
A. Pica
3   Institut de radio-oncologie, Clinique Bois-Cerf, Lausanne, Switzerland
,
A. Schalenbourg
1   Hôpital ophtalmique Jules-Gonin, FAA, Département dʼophtalmologie, Université de Lausanne, Switzerland (Chairman: Prof. Dr. Francine Behar-Cohen)
› Author Affiliations
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Publication History

Publication Date:
26 April 2016 (online)

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Introduction

In 2013, the Stanford Group suggested a low-dose radiation therapy (2 × 2 Gy) for orbital non-Hodgkin lymphoma (NHL), having observed no in-treatment field relapses in 27 treated sites (clinical stage IE-IV), with a complete response (CR) in 23 sites, a partial response (PR) in 3 sites, and steady disease (SD) in 1 site, after a median follow-up of 26 months [1]. We applied this protocol in a case of bilateral conjunctival follicular lymphoma grade I–II.

 

  • References

  • 1 Fasola CE, Jones JC, Huang DD et al. Low-dose radiation therapy (2 Gy X 2) in the treatment of orbital lymphoma. Int J Radiat Oncol Biol Phys 2013; 86: 930-935
    CrossrefPubMedGoogle Scholar
  • 2 Stefanovic A, Lossis IS. Extranodal marginal zone lymphoma of the ocular adnexa. Blood 2009; 114: 501-510
    CrossrefPubMedGoogle Scholar
  • 3 Coupland SE, Chamot L. Tumeurs conjonctivales lymphoproliferatives. In: Zografos L, Desjardins L, Moulin A, eds Tumeurs de la conjonctive. Paris: Edition L – Groupe CIEL, BSOF; 2014: 189-200
    Google Scholar
  • 4 Kirkegaard MM, Coupland SE, Prause JU et al. Malignant lymphoma of the conjunctiva. Surv Ophthalmol 2015; 60: 444-458
    CrossrefPubMedGoogle Scholar
  • 5 Stafford SL, Kozelsky TF, Garrity JA et al. Orbital lymphoma: radiotherapy outcome and complications. Radiother Oncol 2001; 59: 139-144
    CrossrefPubMedGoogle Scholar