RSS-Feed abonnieren
DOI: 10.1055/s-0040-1721731
Carbamazepine-Induced Nonepileptic Myoclonus in a Child with Autism and Epilepsy
Funding None.
Abstract
This study deals with a child with different type of seizures several times in week and unresponsive to antiepileptic drugs. Distinguishing between epileptic seizure and motor tic in a patient diagnosed with epilepsy and autism can be challenging. In this study we presented a male child patient on carbamazepine (CBZ) therapy. In the first days of treatment seizure frequency decreased, but after CBZ treatment dosage reached 15 mg/kg/day (at the 25th day of the treatment), the patient presented to the clinic describing several episodes of myoclonus. There were no changes in electroencephalography during the myoclonus. In follow-up, myoclonus was not described after the cessation of CBZ.
Publikationsverlauf
Eingereicht: 17. September 2020
Angenommen: 03. November 2020
Artikel online veröffentlicht:
20. Januar 2021
© 2021. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
References
- 1 Aguglia U, Zappia M, Quattrone A. Carbamazepine-induced nonepileptic myoclonus in a child with benign epilepsy. Epilepsia 1987; 28 (05) 515-518
- 2 Parmeggiani L, Seri S, Bonanni P, Guerrini R. Electrophysiological characterization of spontaneous and carbamazepine-induced epileptic negative myoclonus in benign childhood epilepsy with centro-temporal spikes. Clin Neurophysiol 2004; 115 (01) 50-58
- 3 Neglia JP, Glaze DG, Zion TE. Tics and vocalizations in children treated with carbamazepine. Pediatrics 1984; 73 (06) 841-844
- 4 Dhuna A, Pascual-Leone A, Talwar D. Exacerbation of partial seizures and onset of nonepileptic myoclonus with carbamazepine. Epilepsia 1991; 32 (02) 275-278
- 5 Magaudda A, Di Rosa G. Carbamazepine-induced non-epileptic myoclonus and tic-like movements. Epileptic Disord 2012; 14 (02) 172-173
- 6 Nanba Y, Maegaki Y. Epileptic negative myoclonus induced by carbamazepine in a child with BECTS. Benign childhood epilepsy with centrotemporal spikes. Pediatr Neurol 1999; 21 (03) 664-667