PDF icon Download PDF
J Knee Surg 2022; 35(01): 021-025
DOI: 10.1055/s-0040-1710546
Original Article

Impact of Parkinson's Disease on Complications, Readmission Rates, and Costs of Care following Primary Total Knee Arthroplasty

Kevin B. Marchand
1   Northwell Health Orthopedics, Lenox Hill Hospital, New York, New York
,
Rushabh Vakharia
2   Department of Orthopedic Surgery, Holy Cross Hospital, Trinity Health, Fort Lauderdale, Florida
,
Nipun Sodhi
3   Northwell Health Orthopedics, Long Island Jewish Medical Center, New York, New York
,
Hiba Anis
4   Department of Orthopedic Surgery, Cleveland Clinic Foundation, Cleveland, Ohio
,
Hytham S. Salem
1   Northwell Health Orthopedics, Lenox Hill Hospital, New York, New York
,
Giles R. Scuderi
1   Northwell Health Orthopedics, Lenox Hill Hospital, New York, New York
,
Michael A. Mont
1   Northwell Health Orthopedics, Lenox Hill Hospital, New York, New York
,
Martin William Roche
2   Department of Orthopedic Surgery, Holy Cross Hospital, Trinity Health, Fort Lauderdale, Florida
› Author Affiliations
› Further Information
   Permissions and Reprints
Preview

Abstract

Large-scale studies evaluating the effects of Parkinson's disease (PD) on primary total knee arthroplasty (TKA) are limited. The purpose of this study was to determine if PD patients undergoing primary TKA have increased: (1) medical complications; (2) implant-related complications; (3) readmission rates; and (4) costs. A query was performed using an administrative claims database. The study group consisted of all patients undergoing primary TKA who had a history of PD. Matched non-PD patients undergoing primary TKA served as a control group. The query yielded 72,326 patients (PD = 18,082; matching cohort = 54,244). Pearson's chi-square tests, logistic regression analyses, and Welch's t-tests were used to test for significance between the cohorts. Primary TKA patients who had PD were found to have greater incidences and odds of medical complications (4.21 vs. 1.24%; odds ratio [OR]: 3.50, 95% confidence interval [CI]: 3.15–3.89, p < 0.0001) and implant-related complications (5.09 vs. 3.15%; OR: 1.64, 95% CI: 1.51–1.79, p < 0.0001) compared with the matching cohort. Additionally, the rates and odds of 90-day readmission were higher (16.29 vs. 12.66%; OR:1.34, p < 0.0001) and episodes of care costs were significantly greater ($17,105.43 vs. $15,252.34, p < 0.0001) in patients who had PD. Results demonstrate that PD patients undergoing primary TKA had higher incidences of medical and implant-related complications. They also had increased 90-day readmission rates and costs compared with controls. The findings of this study should be used in risk stratification and should inform physician–patient discussion but should not be arbitrarily used to deny access to care.

Keywords

knee - osteoarthritis - arthroplasty - Parkinson's disease


Publication History

Received: 03 February 2020

Accepted: 31 March 2020

Article published online:
27 May 2020

© 2020. Thieme. All rights reserved.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA