Abstract
Background Managing research data in biomedical informatics research requires solid data governance
rules to guarantee sustainable operation, as it generally involves several professions
and multiple sites. As every discipline involved in biomedical research applies its
own set of tools and methods, research data as well as applied methods tend to branch
out into numerous intermediate and output data objects, making it very difficult to
reproduce research results.
Objectives This article gives an overview of our implementation status applying the Findability,
Accessibility, Interoperability and Reusability (FAIR) Guiding Principles for scientific
data management and stewardship onto our research data management pipeline focusing
on the software tools that are in use.
Methods We analyzed our progress FAIRificating the whole data management pipeline, from processing
non-FAIR data up to data usage. We looked at software tools for data integration,
data storage, and data usage as well as how the FAIR Guiding Principles helped to
choose appropriate tools for each task.
Results We were able to advance the degree of FAIRness of our data integration as well as
data storage solutions, but lack enabling more FAIR Guiding Principles regarding Data
Usage. Existing evaluation methods regarding the FAIR Guiding Principles (FAIRmetrics)
were not applicable to our analysis of software tools.
Conclusion Using the FAIR Guiding Principles, we FAIRificated relevant parts of our research
data management pipeline improving findability, accessibility, interoperability and
reuse of datasets and research results. We aim to implement the FAIRmetrics to our
data management infrastructure and—where required—to contribute to the FAIRmetrics
for research data in the biomedical informatics domain as well as for software tools
to achieve a higher degree of FAIRness of our research data management pipeline.
Keywords
data quality - data management - data analysis - data linkage
