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Synfacts 2020; 16(05): 0508
DOI: 10.1055/s-0040-1707504

Synthesis of Heterocycles

© Georg Thieme Verlag Stuttgart · New York

Synthesis of Five-Membered Heterocycles by H₃PO₂-Catalyzed Cyclization of Stereodefined Alcohols

Authors

Victor Snieckus
Emma L. McInturff (Pfizer)

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Publication Date:
20 April 2020 (online)

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Key words

stereoselectivity - S_N2 mechanism - tetrahydrofurans - pyrrolidines - phosphinic acid