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Semin Neurol 2020; 40(02): 192-200
DOI: 10.1055/s-0040-1703000
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Multiple Sclerosis in Children: Current and Emerging Concepts

J. Nicholas Brenton
1   Department of Neurology, University of Virginia, Charlottesville, Virginia
,
Ryan Kammeyer
2   Department of Pediatrics, University of Colorado, Aurora, Colorado
3   Department of Neurology, University of Colorado, Aurora, Colorado
,
Lauren Gluck
4   Department of Pediatrics, Yale University, New Haven, Connecticut
,
Teri Schreiner
2   Department of Pediatrics, University of Colorado, Aurora, Colorado
3   Department of Neurology, University of Colorado, Aurora, Colorado
,
Naila Makhani
4   Department of Pediatrics, Yale University, New Haven, Connecticut
5   Department of Neurology, Yale University, New Haven, Connecticut
› Author Affiliations Funding Dr. Makhani was funded by the National Institutes of Health (NIH) and National Institute of Neurological Diseases and Stroke (NINDS) (grant number: K23NS101099).
Further Information

Publication History

Publication Date:
15 April 2020 (online)

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Abstract

Multiple sclerosis is being increasingly recognized and diagnosed in children. In the past several years, advances have been made in diagnosing multiple sclerosis in children, identifying new genetic and environmental risk factors, delineating underlying immunobiology, characterizing imaging findings, and implementing new treatment strategies. In this review, we discuss these advances. Future research into the determinants of multiple sclerosis in children and into new treatment options will be aided by continued international collaboration.

Keywords

multiple sclerosis - children - pediatric
 

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