Abstract
Transfusion-associated acute lung injury (TRALI) is one of the complications seen
due to transfusion. Hypoxemia and bilateral pulmonary infiltration in posteroanterior
chest roentgenogram is seen in all cases during transfusion or within the first 6 hours;
fever, hypotension, and pink frothy bleeding from endotracheal tube may also be seen.
It can be seen following the administration of any blood product. The management strategies
for TRALI include withholding the transfusion, positive pressure breathing support,
and diuretics. There are few reported cases of TRALI occurring following donor granulocyte
transfusion (DGT). In this article, we discuss two cases of TRALI following DGT transfusion.
Keywords
pediatric - donor granulocyte transfusion - TRALI
