Endoscopy 2019; 51(04): S164
DOI: 10.1055/s-0039-1681656
ESGE Days 2019 ePoster podium presentations
Friday, April 5, 2019 16:30 – 17:00: GI bleeding 5 ePoster Podium 6
Georg Thieme Verlag KG Stuttgart · New York

IRRIGATION OF THE INCOMPLETE SILVER SALT OF POLYACRYLIC ACID CONTAINING SILVER NANOPARTICLES IN HEMOSTASIS FOR INTRA-BIOPSY/POLYPECTOMY COLONIC BLEEDING

V Viktor
1   State Scientific Center of Coloproctology, Moscow, Russian Federation
,
S Sergey
1   State Scientific Center of Coloproctology, Moscow, Russian Federation
,
O Olga
1   State Scientific Center of Coloproctology, Moscow, Russian Federation
› Author Affiliations
Further Information

Publication History

Publication Date:
18 March 2019 (online)

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    Aims:

    The endoscopic hemostasis techniques and tools growth in parallel with the new techniques of endoscopic surgery. Clinical endoscopist must be aware of all available hemostatic tool to optimize the management of bleeding in daily practice. This study aims to assess usefulness of the new irrigation technique for intraprocedural colonic bleeding.

    Methods:

    In this preliminary study, we investigated prospectively cases of intraprocedural bleeding occurred in our Department from 2016 to 2018, which applied the new technique of irrigation hemostasis. The bleeding area was irrigated 10 – 30 ml of the 1% fluid of the incomplete silver salt of polyacrylic acid containing silver nanoparticles (does not affect the function of systemic hemostasis, hemostatic affect achieved by forming a polymethacrylate membrane subsequently replaced by fibrin) through a spray-catheter inserted into the endoscope's instrumental channel, exposure time = 1 – 2 min. In case of continued bleeding additional hemostasis was carried out (mechanical or/and thermal hemostatic methods). Comparative analysis: Fisher's two-tailed exact test.

    Results:

    A total of 22 procedures were analyzed (9 intra-biopsy1 group, 13 intra-polypectomy2 group). No technique-related systemic side effects were observed.

    Group 1: during the formation of the polymer complex occurs hemostasis in 9 cases, hemostatic effect achieved in 1 – 2 min, repeated bleeding was not existed, effectiveness – 100%.

    Group 2: forming a smooth elastic surface didn't break visualization of the source of bleeding and convenient field for further effective hemostatic manipulations. Additional methods of hemostasis were performed significantly more often in the group 2 (F = 0.00552, p < 0.05). The method of polypectomy was not associated with the subsequent need for additional hemostasis.

    Conclusions:

    These data revealed the effectiveness of the new irrigation hemostasis technique for intra-biopsy bleeding. Further analysis is required to determine the capabilities of this irrigation technique in hemostasis for intra-polypectomy colonic bleeding.