J Pediatr Intensive Care 2018; 07(04): 188-195
DOI: 10.1055/s-0038-1656535
Original Article
Georg Thieme Verlag KG Stuttgart · New York

Presence of Invasive Devices and Risks of Healthcare-Associated Infections and Sepsis

Erin E. Bennett
1   Division of Critical Care, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States
,
John VanBuren
1   Division of Critical Care, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States
,
Richard Holubkov
1   Division of Critical Care, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States
,
Susan L. Bratton
1   Division of Critical Care, Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States
› Author Affiliations
Funding The University of Utah supported the project with salary support for employee effort for statistical analysis.
Further Information

Publication History

06 March 2018

24 April 2018

Publication Date:
23 May 2018 (online)

Abstract

The present study evaluated the daily risk of healthcare-associated infections and sepsis (HAIS) events in pediatric intensive care unit patients with invasive devices. This was a retrospective cohort study. Invasive devices were associated with significant daily risk of HAIS (p < 0.05). Endotracheal tubes posed the greatest risk of HAIS (hazard ratio [HR]: 4.39, confidence interval [CI]: 2.59–7.46). Children with both a central venous catheter (CVC) and urinary catheter (UC) had over 2.5-fold increased daily risk (HR: 2.59, CI: 1.18–5.68), in addition to daily CVC risk (HR: 3.06, CI: 1.38–6.77) and daily UC risk (HR: 8.9, CI: 3.62–21.91). We conclude that a multistate hazard model optimally predicts daily HAIS risk.

 
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