Self-Coagulogram

Summary

A curve named “self-coagulogram” and obtained by means of the “self thromboplastin-prothrombin time” is described. The beginning of the curve reflects clot formation dynamics, while the tail reflects the fibrinolytic activity. The self-coagulogram helps the detection of hemorrhagic syndromes, the evaluation of anticoagulant therapy and fibrinolytic activity, natural or induced. It is a very simple and practical method.

• References

• 1 Kugelmass I. N. Contribution physico-chimique au mécanisme de la coagulation du sang. Arch. int. Physiol. 21: 139 1923;
• 2 Foster R. H. K. A graphie method for measuring the clotting time of blood. J. Lab. clin. Med. 16: 505 1930; /31
• 3 Hartert H. Blutgerinnungsstudien mit der Thrombélastographie einem Venen – Unter suchungs -verfahren. Klin. Wschr. 26: 577 1948;
• 4 Hartert H. Die Thrombélastographie. Z. ges. exp. Med. 117: 189 1951;
• 5 von Kaulla K. N. Methods for recording blood coagulation. In: Progress in Hematology III. 231 Grane and Stratton; New York: 1962
• 6 Berkarda B, Derman U. Self thromboplastin-prothrombin zamani. Türk Tip Cem. Med. 29: 433 1963;
• 7 Berkarda B, Derman U. Self thromboplastin-prothrombin time. A new test in hemorrhagic syndromes and in the control of anticoagulant therapy. Thrombos. Diathes. Haemorrh. (Stuttg.) 11: 468 1964;
• 8 Buckell M. The effect of citrate on euglobulin methods of estimating fibrinolytic activity. J. clin. Path. 11: 403 1958;
• 9 Jung E. G, Duckert F. Action of fibrinolytic on coagulation factors. Schweiz. med. Wschr. 90: 1239 1960;