Thromb Haemost 1966; 16(03/04): 732-737
DOI: 10.1055/s-0038-1655658
Originalarbeiten — Original Articles — Travaux Originaux
Schattauer GmbH

Studies of the Coagulation and Prothrombin Time in the Mouse Embryo

R Caruso
1   Departments of Preventive Medicine and Medicine and the Cancer Research Institute, University of California School of Medicine, San Francisco
,
N. L Petrakis
1   Departments of Preventive Medicine and Medicine and the Cancer Research Institute, University of California School of Medicine, San Francisco
› Author Affiliations

This work was supported by research grants #5T5 GM 43-03 and CA-05485 (4) from the Division of Research Grants, National Institutes of Health, U. S. Public Health Service.
Further Information

Publication History

Publication Date:
26 June 2018 (online)

Preview

Summary

Thirteen- to sixteen-day mouse embryos (Witschi stages 30–34) were tested for whole blood coagulation and prothrombin times. Both times were found to be significantly longer in the embryos than in the adults, the times decreasing with embryonic development. The significance of these resluts was discussed in terms of reported research on other animals.