Summary
Two patients with congenital factor-V deficiency and a third with a combined deficiency
of factor V and factor VIII are described. Under cover of fresh frozen plasma, tooth
extractions were performed on two of these patients and spontaneous bleeding arrested.
It is concluded that the achievement of a blood level of factor V of 20 per cent once
daily is sufficient to assure adequate haemostasis. A low recovery of factor V activity
in the plasma following infusion was found. However, in spite of this, adequate blood
levels were easily attained due to the excellent preservation of factor V activity
in the stored fresh frozen plasma.
