Summary
Two amphipathic alcohols, benzyl alcohol and phenol, have been found to diminish adhesiveness
of platelets to glass beads and to impair adenosine diphosphate (ADP)-induced platelet
aggregation, while ethanol and isopropanol, both completely water soluble, had no
inhibitory effects. Comparatively, phenol is a more potent inhibitor than benzyl alcohol.
It is suggested that the basis for their antiadhesive effect may be similar to that
which underlies their local anesthetic properties.
