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Thromb Haemost 1977; 38(04): 1002-1009
DOI: 10.1055/s-0038-1651918
DOI: 10.1055/s-0038-1651918
Original Article
Malondialdehyde Production by Platelets during Secondary Aggregation
Further Information
Publication History
Publication Date:
04 July 2018 (online)
Summary
A method is described for increasing the sensitivity of the thiobarbiturate assay for malondialdehyde by concentrating the coloured reaction product. The basal level of malondialdehyde-like material in plasma was found to be about 0.03 μM. Platelets synthesized malondialdehyde when stimulated by collagen or thrombin and also during the second phase of aggregation induced by ADP or adrenaline.
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