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Semin Neurol 2018; 38(02): 238-246
DOI: 10.1055/s-0038-1649334
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Global Health Neurology: HIV/AIDS

Payal B. Patel
1   Division of Neuro-infectious Disease Clinical Research, Department of Neurology, Yale University, New Haven, Connecticut
,
Serena S. Spudich
2   Division of Neurological Infections and Global Neurology, Department of Neurology, Yale University, New Haven, Connecticut
› Author Affiliations
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Publication History

Publication Date:
23 May 2018 (online)

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Abstract

With the advent of combination antiretroviral therapies, the mortality rate from HIV has declined, while the prevalence of long-term HIV-related neurologic complications continues to rise. Thirty-six million individuals are living with HIV around the world, many of whom reside in resource-limited settings. The majority of studies have focused on individuals residing in the developed world, while the impact of HIV disproportionately affects people living in developing countries. This review focuses on recent domestic and international studies regarding neurologic complications related to HIV, including opportunistic infections, peripheral neuropathy, cerebrovascular disease, and HIV-associated neurocognitive disorders, in light of the growing population affected by these conditions.

Keywords

human immunodeficiency virus - global health - HIV-associated neurocognitive disorders - peripheral neuropathy - cerebrovascular disease