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Thromb Haemost 1973; 30(02): 363-370
DOI: 10.1055/s-0038-1649086
DOI: 10.1055/s-0038-1649086
Original Article
A 3.5-Second Phenomenon in Haemostasis
A Scanning Electron Microscopic StudyFurther Information
Publication History
Received for publication
08 June 1973
Accepted for publication
27 June 1973
Publication Date:
30 June 2018 (online)
Summary
Experiments with injury of the abdominal rat skin were carried out to examine the haemostatic system mechanism in vivo after zero to 30 seconds bleeding time. In the bleeding area only a few platelet aggregates could be found with no primary platelet thrombus. After 3.5 second bleeding time the first fibrin strands have been observed at the site of injury. The hypothesis is put forward that there is a very fast reacting haemostatic mechanism which results in the fibrin formation already at 3.5 seconds.
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