Respiratory Support in Bronchiolitis: Trial Evidence

Steve Cunningham

doi:10.1055/s-0038-1637765

American Journal of Perinatology, Table of Contents

Am J Perinatol 2018; 35(06): 553-556
DOI: 10.1055/s-0038-1637765

Review Article

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Respiratory Support in Bronchiolitis: Trial Evidence

Steve Cunningham

¹Department of Paediatric Respiratory Medicine, MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom

› Author Affiliations

Abstract

Acute viral lower respiratory tract infection is frequently associated with hypoxemia and respiratory distress, sometimes progressing to hypercarbia and respiratory failure. In recent years, trials have assessed the effects of oxygen supplementation and respiratory support with high-flow oxygen therapy. An oxygen saturation target of 90% is as safe and clinically effective as 94% in infants with bronchiolitis. Trials of high-flow humidified oxygen have demonstrated safety, but as yet poorly demarcated an appropriate place for use within the clinical course of the disease. Effective trials of continuous positive airway pressure are lacking and urgently required. The trials reported to date have highlighted the need for common outcomes in relation to treatment failure.

Keywords

bronchiolitis - oxygen - CPAP - high flow oxygen therapy

Full Text

References

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