Body Surface Laplacian Mapping of Bioelectrical Activity

Abstract:

A method is described to process and interpret multi-channel bioelectrical signals. The bioelectrical signals were recorded noninvasively over the body surface of human subjects at 120 sites. The body surface Laplacian maps were then constructed from the multi-channel bioelectrical potential measurement. The method was evaluated by means of computer simulations, and applied to imaging cardiac electrical activity. The present investigation suggests body surface Laplacian mapping provides an important means in interpreting bioelectrical signals.

Keywords:

Body Surface Laplacian Mapping - BSLM - BSPM - Electrocardiography

• REFERENCES

• 1 Taccardi Distribution of heart potential on the thoracic surface of normal human subjects. Circ Res 1963; 12: 341-52.
• 2 Mirvis F, Keller W, Ideker RE, Cox JW, Zettergren DG, Dowdie RF. “Values and limitations of surface isopotential mapping techniques in the detection and localization of multiple discrete epicardial events”. J Electrocardiol 1977; Vol 10: 347-58.
• 3 Rudy Y, Plonsey R. “A comparison of volume conductor and source geometry effects on body surface and epicardial potentials.”. Circ Res 1980; Vol 46: 283-91.
• 4 Hjorth B. An on-line transformation of EEG scalp potentials into orthogonal source derivations. Electroenceph Clin Neurophysiol 1975; Vol 39: 526-30.
• 5 He B, Cohen RJ. Body Surface ECG Laplacian Mapping. IEEE Trans Biomed Eng 1992; Vol BME-39: 1179-91.
• 6 He B, Cohen RJ. Body surface Laplacian mapping of cardiac electrical activity. Am J Cardiol 1992; Vol 70: 1617-20.
• 7 He B, Parati G, Yin JZ, Cohen RJ. “Detecting cardiac activation sequence from body surface Laplacian maps.”. Journal of Electrocardiology 1992; Suppl: 109-10.
• 8 He B, Kirby DA, Mullen T, Cohen RJ. Body surface Laplacian mapping of cardiac excitation in intact pigs. PACE 1993; 16 (Part I): 1017-26.
• 9 Ono J, Yin Z, He B, Cohen RJ. “A 3-D computer simulation study of body surface Laplacian ECG maps: Myocardial infarction.”. Proc IEEE/EMBS 1993; 804-5.
• 10 Rosenbaum D, He B, Cohen RJ. “New approaches for evaluating cardiac electrical activity: Repolarization alternans and body surface Laplacian imaging.”. In: Cardiac Electrophysiology. Zipes, et al. (eds) 1994: 1187-97.
• 11 He B, Chernyak Y, Cohen RJ. “An equivalent body surface charge model representing three dimensional bioelectrical activity.”. IEEE Transactions on Biomedical Engineering 1995; Vol 42: 637-46.
• 12 Yu X, He B. t“Laplacian electrocardiographic imaging: A model study.” SPIE Proceedings 1995; Vol 2622: 746-50.
• 13 Wei D, Harasawa E, He B. “Simulated body surface potential and Laplacian maps during the left ventricular breakthrough.”. Proc IEEE/EMBS. 1995
• 14 He B. Laplacian Electrocardiography. Med and Biol Eng and Comput 1996; Vol 34 (Suppl. 01) (Part 2): 29-30.
• 15 He B, Cohen RJ. Body surface Laplacian electrocardiographic mapping - A review. Critical Review in Biomedical Engineering 1995; 23: 475-510.
• 16 He B, Wu D. “A Bioelectric Inverse Imaging Technique Based on Surface Laplacians.”. IEEE Trans BME 1997; 44: 529-38.
• 17 Wang Y, Wu D, He B. “On the Algorithm for Computing Body Surface Laplacians in an Inhomogeneous Volume Conductor with Arbitrary Shape.”. IEEE Trans BME. (in press).