Methods Inf Med 1991; 30(01): 15-22
DOI: 10.1055/s-0038-1634813
Original Articles
Schattauer GmbH

Bayesian Diagnostic Probabilities without Assuming Independence of Symptoms

A. Gammerman
1   Computer Science Department, Heriot-Watt University, Edinburgh, U.K
,
A. R. Thatcher
2   New Maiden, Surrey, U.K
› Institutsangaben
We wish to thank Mr. S. J. Nixon MB, ChB, BSc, FRCS of the General Surgical Unit, Western General Hospital, Edinburgh, and Dr. A. A. Gunn, formerly of the Bangour Hospital, Roxburgh, for their expert advice and for making available data originally collected at Bangour Hospital. We also wish to thank Yiqun Gu r’cor writing computer programs and Jlbyce Smith for typesetting this paper.
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Publikationsdatum:
08. Februar 2018 (online)

The paper describes an application of Bayes’ Theorem to the problem of estimating from past data the probabilities that patients have certain diseases, given their symptoms. The data consist of hospital records of patients who suffered acute abdominal pain. For each patient the records showed a large number of symptoms and the final diagnosis, to one of nine diseases or diagnostic groups. Most current methods of computer diagnosis use the “Simple Bayes” model in which the symptoms are assumed to be independent, but the present paper does not make this assumption. Those symptoms (or lack of symptoms) which are most relevant to the diagnosis of each disease are identified by a sequence of chi-squared tests. The computer diagnoses obtained as a result of the implementation of this approach are compared with those given by the “Simple Bayes” method, by the method of classification trees (CART), and also with the preliminary and final diagnoses made by physicians.

 
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