Quantitative Blood Velocity Mapping in Glomerular Capillaries by in vivo Observation with an Intravital Videomicroscope

Y. Ogasawara; K. Takehara; T. Yamamoto; R. Hashimoto; H. Nakamoto; F. Kajiya

doi:10.1055/s-0038-1634269

Methods of Information in Medicine, Inhaltsverzeichnis

Methods Inf Med 2000; 39(02): 175-178
DOI: 10.1055/s-0038-1634269

Original Article

Schattauer GmbH

Quantitative Blood Velocity Mapping in Glomerular Capillaries by in vivo Observation with an Intravital Videomicroscope

Y. Ogasawara

¹Dept. of Medical Engineering, Kawasaki Medical School, Kurashiki, Japan

,

K. Takehara

²Dept. of Electronic Engineering, Okayama University of Science, Okayama, Japan

,

T. Yamamoto

¹Dept. of Medical Engineering, Kawasaki Medical School, Kurashiki, Japan

,

R. Hashimoto

²Dept. of Electronic Engineering, Okayama University of Science, Okayama, Japan

,

H. Nakamoto

¹Dept. of Medical Engineering, Kawasaki Medical School, Kurashiki, Japan

,

F. Kajiya

¹Dept. of Medical Engineering, Kawasaki Medical School, Kurashiki, Japan

› Institutsangaben

Abstract

Abstract:

We have evaluated rat glomerular microcirculation under in-vivo condition with an intravital videomicroscope. To measure erythrocyte velocities, a line segment was set along the glomerular capillaries in time-sequential videotaped images and then a spatiotemporal image was constructed along that segment. The angle of striped pattern in the spatio-temporal image which reflects the erythrocyte velocity, was estimated to compute erythrocyte velocity vector mapping. We found that erythrocyte velocities in rat glomeruli were significantly faster in diabetic rats than in control rats (p <0.05). In conclusion, we have succeeded in quantitatively evaluating the in-vivo renal microcirculation with our videomicroscope system and by spatiotemporal image analyzing method.

Keywords:

Erythrocyte Velocity - Glomerulus - Renal Microcirculation - Spatiotemporal Image - Velocity Mapping

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Referenzen

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