Nervenheilkunde 2018; 37(01): 17-19
DOI: 10.1055/s-0038-1631166
Kopfschmerz
Schattauer GmbH

Symptomatische Kopfschmerzen

Eine EinführungSymptomatic headachesAn introduction
V. Mylius
1   Klinik für Neurologie und Neurorehabilitation, Valens, Schweiz
3   Philipps-Universität Marburg, Klinik für Neurologie, Marburg
4   Klinik für Neurologie, Kantonsspital St. Gallen, St. Gallen, Schweiz
,
M. Teepker
2   Hardtwaldklinik, Bad Zwesten
3   Philipps-Universität Marburg, Klinik für Neurologie, Marburg
› Author Affiliations
Further Information

Publication History

eingegangen am: 02 October 2017

angenommen am: 20 October 2017

Publication Date:
09 February 2018 (online)

Zusammenfassung

Kopfschmerzen werden in idiopathische bzw. symptomatische Formen unterschieden; die International Headache Society (IHS) hat hierfür Kriterien definiert. Die idiopathischen Erkrankungen werden dabei phänomenologisch unterschieden, die symptomatischen anhand ihrer Ätiologie. Diese Differenzierung ist sinnvoll, da bei symptomatischen Kopfschmerzen mitunter eine kausale Therapie möglich ist.

Aufgrund von Gemeinsamkeiten hinsichtlich ihrer Klinik, Pathophysiologie und Therapie sind die Grenzen zwischen diesen Kopfschmerzgruppen aber nicht immer eindeutig. In einigen Fällen wurde eine Neubewertung hinsichtlich einer idiopathischen bzw. symptomatischen Genese notwendig.

Summary

Headaches can be divided in idiopathic and symptomatic forms according to criteria defined by the International Headache Society (IHS). The idiopathic forms are differentiated phenomenologically, the symptomatic ones according to their etiology. This determination is reasonable as the cause of headaches can be treated in symptomatic diseases.

There are common features concerning clinical presentation, pathophysiology und therapy for both, idiopathic and symptomatic headaches. Thus, it may be difficult to clearly set boundaries between these headache groups. For some headache, a rereappraisal (idiopathic vs. symptomatic) was necessary.

 
  • Literatur

  • 1 The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia 2013; 33 (09) 629-808.
  • 2 Göbel H, Petersen-Braun M, Soyka D. The epidemiology of headache in Germany: A nationwide survey of a representative sample on the basis of the headache classification of the International Headache Society. Cephalalgia 1994; 14 (02) 97-106.
  • 3 Schankin CJ, Straube A, Bassetti CL, Fischer U. Kopfschmerz in der Notaufnahme. Nervenarzt 2017; 88 (06) 597-606.
  • 4 D’Onofrio F, Russo A, Conte F, Casucci G, Tessitore A, Tedeschi G. Post-traumatic headaches: An epidemiological overview. Neurol Sci 2014; 35 Suppl (Suppl. 01) 203-6.
  • 5 Lucas S. Posttraumatic Headache: Clinical characterization and management. Curr Pain Headache Rep 2015; 19 (10) 48.
  • 6 Schankin CJ, Ferrari U, Reinisch VM, Birnbaum T, Goldbrunner R, Straube A. Characteristics of brain tumour-associated headache. Cephalalgia 2007; 27 (08) 904-11.
  • 7 Kahn K, Finkel A. It is a tumor – current review of headache and brain tumor. Curr Pain Headache Rep 2014; 18 (06) 421.
  • 8 Jürgens TP, Busch V, Schmidt-Wilcke T, Schuierer G, Leinisch E, May A. Migraine-like headache in intracranial haemorrhage is alleviated by sumatriptan and almotriptan. Cephalalgia 2008; 28 (03) 302-4.
  • 9 Taylor LP. Mechanism of brain tumor headache. Headache 2014; 54 (04) 772-5.
  • 10 Ruff RL, Blake K. Pathophysiological links between traumatic brain injury and post-traumatic headaches. F1000Res 2016; 5.
  • 11 Goadsby PJ, Holland PR, Martins-Oliveira M, Hoffmann J, Schankin C, Akerman S. Pathophysiology of migraine: A disorder of sensory rocessing. Physiol Rev 2017; 97 (02) 553-622.
  • 12 Welch KM. Current opinions in headache pathogenesis: introduction and synthesis. Curr Opin Neurol 1998; 11 (03) 193-7.
  • 13 Zielman R, Wijnen JP, Webb A, Onderwater GLJ, Ronen I, Ferrari MD. et al. Cortical glutamate in migraine. Brain 2017; 140 (07) 1859-71.
  • 14 Srikiatkhachorn A, Le Grand SM, Supornsilpchai W, Storer RJ. Pathophysiology of medication overuse headache – an update. Headache 2014; 54 (01) 204-10.
  • 15 Leao AAP. Spreading depression of activity in the cerebral cortex. J Neurophysiol 1944; 07: 359-90.
  • 16 Hadjikhani N, Sanchez Del Rio M, Wu O, Schwartz D, Bakker D, Fischl B. et al. Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proc Natl Acad Sci USA 2001; 98 (08) 4687-92.
  • 17 Welch KMA. Contemporary concepts of migraine pathogenesis. Neurology 2003; 61 (08) Suppl (Suppl. 04) S2-8.
  • 18 Pielsticker A, Haag G, Zaudig M, Lautenbacher S. Impairment of pain inhibition in chronic tensiontype headache. Pain 2005; 118 (1–2): 215-23.
  • 19 Schmidt-Wilcke T, Gänssbauer S, Neuner T, Bogdahn U, May A. Subtle grey matter changes between migraine patients and healthy controls. Cephalalgia 2008; 28 (01) 1-4.
  • 20 Schmidt-Wilcke T, Leinisch E, Straube A, Kämpfe N, Draganski B, Diener HC. et al. Gray matter decrease in patients with chronic tension type headache. Neurology 2005; 65 (09) 1483-6.
  • 21 Holle D, Naegel S, Krebs S, Gaul C, Gizewski E, Diener H-C. et al. Hypothalamic gray matter volume loss in hypnic headache. Ann Neurol 2011; 69 (03) 533-9.
  • 22 Schwedt TJ, Chong CD. Medication overuse headache: Pathophysiological insights from structural and functional brain MRI research. Headache 2017; 57 (07) 1173-8.
  • 23 Abend NS, Nance ML, Bonnemann C. Subcutaneous sumatriptan in an adolescent with acute posttraumatic headache. J Child Neurol 2008; 23 (04) 438-40.
  • 24 Manfredi PL, Shenoy S, Payne R. Sumatriptan for headache caused by head and neck cancer. Headache 2000; 40 (09) 758-60.
  • 25 Diener H-C, Berlit P, Arendt G. (Hrsg.) Leitlinien für Diagnostik und Therapie in der Neurologie. Stuttgart: Thieme; 2002
  • 26 Gelfand AA, Gelfand JM, Prabakhar P, Goadsby PJ. Ophthalmoplegic “migraine” or recurrent ophthalmoplegic cranial neuropathy: New cases and a systematic review. J Child Neurol 2012; 27 (06) 759-66.
  • 27 Ophoff RA, Terwindt GM, Vergouwe MN, van Eijk R, Oefner PJ, Hoffman SM. et al. Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4. Cell 1996; 87 (03) 543-52.
  • 28 Fusco de M, Marconi R, Silvestri L, Atorino L, Rampoldi L, Morgante L. et al. Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump alpha2 subunit associated with familial hemiplegic migraine type 2. Nat Genet 2003; 33 (02) 192-6.
  • 29 Dichgans M, Freilinger T, Eckstein G, Babini E, Lorenz-Depiereux B, Biskup S. et al. Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. Lancet 2005; 366 (9483): 371-7.