Summary
Objectives
: The intrauterine growth restriction (IUGR) is a pathological state: the fetus is
at risk of hypoxia and this condition is associated with increased perinatal morbidity
and mortality. However, evidence-based guidelines for clinical surveillance are poor
and lack reliable indexes. This study introduces new procedures to extract parameters
from the fetal heart rate signal in order to identify severe intrauterine growth restricted
(IUGR) fetuses
Methods
: Standard parameters (time domain and frequency domain indexes) are compared to a
new parameter, the Lempel Ziv complexity, and to two regularity estimators (approximate
entropy and sample entropy). The paper analyzes the robustness of the indexes coming
from the parameter extraction procedure.
Results and Conclusions
: The results show that the LZ complexity is a stable parameter and it is able to
significantly discriminate the severe IUGR (preterm delivered) from moderate IUGR
(at term delivered) and from healthy fetuses.
Keywords
Complexity - fetal heart rate - IUGR - Lempel Ziv complexity - parameter extraction