Efficiency of in vivo Labeling of Red Blood Cells with^99mTc

Summary

The effectiveness of three commercial bone scintigraphic agents and freshly made stannous chloride in labeling erythrocytes with ^99mTc was compared. Our results indicate that tin pyrophosphate is the agent of choice and that it is most effective when injected at least 15 minutes before the ^99mTc-per-technetate is administered. This technique of labeling red blood cells in vivo could be applied in performing blood pool studies.

Wir verglichen die Wirksamkeit dreier handelsüblicher Kits für die Knochenszintigraphie und neu hergestellten Zinnchlorids zur Markierung von Erythrozyten mit Tc. Unsere Versuche ergaben, daß Zinnpyrophosphat das am besten geeignete Präparat ist und daß es am besten wirkt, wenn es mindestens 15 Minuten vor der ^99mTc-Pertechnat-Gabe injiziert wird. Diese Technik der roten Blutkörperchen-Markierung „in vivo“ könnte bei Blutpooluntersuchungen angewendet werden.

• References

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