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Tierarztl Prax Ausg G Grosstiere Nutztiere 2013; 41(06): 387-391
DOI: 10.1055/s-0038-1623199
Case Report
Schattauer GmbH

Perosomus elumbis in a Holstein calf infected with bovine viral diarrhea virus

Perosomus elumbis bei einem Holstein-Kalb, infiziert mit dem Virus der bovinen Virusdiarrhö
E. Karakaya
1   Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Gorukle, Bursa, Turkey
,
G. Alpay
2   Department of Virology, Faculty of Veterinary Medicine, Gorukle, Bursa, Turkey
,
G. Yilmazbas-Mecitoglu
1   Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Gorukle, Bursa, Turkey
,
A. Alasonyalilar-Demirer
3   Department of Pathology, Faculty of Veterinary Medicine, Gorukle, Bursa, Turkey
,
B. Akgul
4   Department of Surgery, Faculty of Veterinary Medicine, Gorukle, Bursa, Turkey
,
S. Inan-Ozturkoglu
3   Department of Pathology, Faculty of Veterinary Medicine, Gorukle, Bursa, Turkey
,
M. O. Ozyigit
3   Department of Pathology, Faculty of Veterinary Medicine, Gorukle, Bursa, Turkey
,
D. Seyrek-Intas
4   Department of Surgery, Faculty of Veterinary Medicine, Gorukle, Bursa, Turkey
,
K. Seyrek-Intas
1   Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Gorukle, Bursa, Turkey
,
K. Yesilbag
2   Department of Virology, Faculty of Veterinary Medicine, Gorukle, Bursa, Turkey
,
A. Gumen
1   Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Gorukle, Bursa, Turkey
,
A. Keskin
1   Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Gorukle, Bursa, Turkey
› Author Affiliations
Further Information

Publication History

Received: 22 March 2013

Accepted after revision: 06 August 2013

Publication Date:
05 January 2018 (online)

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Summary

The detection of bovine viral diarrhea virus (BVDV) in a female Holstein calf presented with perosomus elumbis, a congenital anomaly, is reported here. A cow with dystocia was evaluated and an abnormal dead calf was detected during vaginal examination. The calf was retrieved via caesarean section and exhibited abnormalities characteristic of PE, such as vertebral and pelvic malformations. These abnormalities were further confirmed using radiographic and necropsy examinations. At necropsy cerebellar hypoplasia was an additional finding, which is a typical lesion associated with bovine virus diarrhea (BVD). Several tissue samples from the calf were tested for the presence of antigens of BVDV and bovine herpesvirus-1 (BHV-1) by ELISA. In addition, sera samples from the dam and calf were tested for the presence of antibodies against BVDV, BHV-1, and bluetongue disease virus (BTV) using a virus neutralization assay. Results indicated that the calf was congenitally infected with BVDV, whereas there was no evidence for the presence of BHV-1 and BTV. In the dam’s serum no antibodies against BVDV, BHV-1, and BTV were detected. Even though the etiology of perosomus elumbis is unknown, BVDV, which causes fetal anomalies at early gestation in cows, may have been a contributing factor in this case.

Zusammenfassung

Der Fallbericht beschreibt die seltene kongenitale Anomalie Perosomus elumbis bei einem neugeborenen weiblichen Holstein-Kalb. Bei der vaginalen Untersuchung einer Kuh mit Geburtsstörungen wurde ein toter, abnormaler Fetus festgestellt. Das mittels Kaiserschnitt entwickelte Kalb wies typische Abnormalitäten im Sinne eines Perosomus elumbis wie Malformationen der Wirbelsäule und des Beckens auf. Die radiologische und pathologische Untersuchung bestätigte diese Veränderungen. Bei der pathologischen Untersuchung fiel eine zerebelläre Hypoplasie auf, die eine typische Läsion im Rahmen der bovinen Virusdiarrhö (BVD) darstellt. Verschiedene Gewebeproben des Kalbes wurden mittels ELISA auf Antigene des BVD-Virus (BVDV) und des bovinen Herpesvirus 1 (BHV-1) untersucht. Zusätzlich erfolgte die Untersuchung von Serumproben der Kuh und des Kalbes mit einem Virusneutralisationstest auf Antikörper gegen BVDV, BHV-1 und das Virus der Blauzungenkrankheit (BTV). Die Ergebnisse zeigten eine kongenitale İnfektion des Kalbes mit dem BVDV, während es keine Anzeichen für eine Infektion mit BHV-1 und BTV gab. Im Serum des Muttertieres ließen sich keine Antikörper gegen BVDV, BHV-1 und BTV nachweisen. Obgleich die Ursache der Missbildung Perosomus elumbis nicht bekannt ist, könnte die BVDV-Infektion, die bei Kühen in der frühen Trächtigkeitsphase fetale Abnormitäten verursacht, in diesem Fall ein beitragender Faktor gewesen sein.

Key words

Cattle - congenital malformations - Perosomus elumbis - bovine viral diarrhea virus

Schlüsselwörter

Rind - kongenitale Missbildungen - Perosomus elumbis - bovine Virusdiarrhö
 

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