Nuklearmedizin 1978; 17(03): 95-98
DOI: 10.1055/s-0037-1620676
Originalarbeiten – Original Articles
Schattauer GmbH

Iron-Dextran Enhancement of 67Ga-Concentration in Abscess Relative to Normal Tissue

Relative Erhöhung der 67Ga-Konzentration in Abszessen durch Eisen-Dextran
S. M. Larson
1   From the Nuclear Medicine Section, Veterans Administration Hospital; the Department of Radiology and Division of Nuclear Medicine, University Hospital, Seattle, Wash, and the Nuclear Medicine Section, Veterans Administration Hospital, Portland, Ore., U.S.A.
,
D. Mahler
1   From the Nuclear Medicine Section, Veterans Administration Hospital; the Department of Radiology and Division of Nuclear Medicine, University Hospital, Seattle, Wash, and the Nuclear Medicine Section, Veterans Administration Hospital, Portland, Ore., U.S.A.
,
D.R. Allen
1   From the Nuclear Medicine Section, Veterans Administration Hospital; the Department of Radiology and Division of Nuclear Medicine, University Hospital, Seattle, Wash, and the Nuclear Medicine Section, Veterans Administration Hospital, Portland, Ore., U.S.A.
› Author Affiliations
Further Information

Publication History

Received: 21 April 1978

Publication Date:
09 January 2018 (online)

Preview

Iron-dextran (Imferon®) significantly increases the concentration of 67Ga in abscess relative to muscle, when given intravenously to abscess bearing rabbits 24 hr after intravenous, carrier-free 67Ga-citrate. This increase is achieved by accelerating the clearance of 67Ga from the blood.

Wenn Kaninchen Eisen-Dextran intravenös nach Gabe von trägerfreiem 67Ga-Zitrat verabreicht wird, erhöht es die 67Ga-Konzentration in Abszessen, bezogen auf Muskelgewebe, signifikant. Diese Erhöhung wird durch Beschleunigung der 67Ga-Clearance aus dem Blut bewirkt.