Lipide und Lipoproteine bei Adipositas und bei Gewichtsreduktion

Zusammenfassung

Bei Adipositas finden sich erhöhte Triglyzerid- spiegel und niedrige HDL-Cholesterin-Konzentrationen.

Trotz Adipositas sind Serumcholesterin-und LDL-Cholesterin-Konzentrationen oft normal. Erfolgreiche Gewichtsreduktion führt zu einer Verbesserung dieser Dyslipoproteinämie, unabhängig von der angewandten Therapie (Diät, VLCD, Medikamente, Adipositaschirurgie). Die Konzentration der AOPPs (Advanced Oxidation Protein Products) fällt unter Gewichtsreduktion signifikant ab. Erfolgreiche Adipositastherapie senkt das Risiko für kardiovaskuläre Erkrankungen durch Senkung der Lipid-, Lipoprotein- und AOPPs-Konzentrationen.

Summary

Hyperlipoproteinemia and dyslipoproteinemia in obese persons is characterized by elevated fasting triglycerides and decreased HDL-cholesterol-levels.

Total cholesterol- and LDL-cholesterol-levels are quite normal in comparison with normalweight people.

Successful weight-reduction induced an improvement of dyslipoproteinemia independent of the applied treatment method (diet, VLCD, drugs, surgery).

The concentration of advanced oxidation protein products (AOPPs) felt down during weight-reduction significantly.

Obesity treatment reduces the risk for coronary and vascular events lowering lipids and lipoproteins and AOPPs.

Schlüsselwörter

Adipositas - Lipide - Lipoproteine - Gewichtsreduktion

Keywords

Obesity - lipids - lipoproteins - weight-reduction

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