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Thromb Haemost 1999; 82(02): 656-661
DOI: 10.1055/s-0037-1615893
DOI: 10.1055/s-0037-1615893
Research Article
Immunology of the Antiphospholipid Syndrome: Antibodies, Antigens, and Autoimmune Response
Authors
Further Information
Publication History
Publication Date:
09 December 2017 (online)
Introduction
The antiphospholipid syndrome (APS) is an autoimmune condition in which a group of autoantibodies are thought to play a direct role in the pathogenesis of thrombosis, fetal loss, and other clinical manifestations. This review will focus on the nature of these autoantibodies, the antigens they recognize, and mechanisms that may contribute to autoimmunity and the production of autoantibodies in patients with APS.
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