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Thromb Haemost 2004; 92(03): 486-494
DOI: 10.1055/s-0037-1613739
DOI: 10.1055/s-0037-1613739
Theme Issue Article
Murine thrombosis models
Financial support: This work was supported by NIH grants HL65224 and HL57346 (WPF) and by NIH T32 Training Grant HL07853 (SMD).
Further Information
Publication History
Received
14 May 2004
Accepted after revision
28 June 2004
Publication Date:
15 December 2017 (online)
Summary
Due to exciting advances in molecular biology, the laboratory mouse has become an important and frequently used model for studying thrombosis. This article reviews several experimental approaches that have been used to study arterial, venous, and microvascular thrombosis in mice. The advantages and limitations of different models are examined. Related topics of mouse anesthesia, phlebotomy, and in vitro hemostasis testing are also reviewed.
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