RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml
Synfacts 2018; 14(01): 0037
DOI: 10.1055/s-0036-1591077
DOI: 10.1055/s-0036-1591077
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
Gold(I)-Catalyzed Stereoselective Synthesis of Deoxyglycosides
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
15. Dezember 2017 (online)
Significance
Deoxyhexose structures can be found in a wide range of natural products. The authors have developed an α-stereoselective catalytic synthesis of deoxyglycosides from glycals by using Au(I)/AgOTf.
#
Comment
The reaction can be applied to a broad range of glycals and alcohols to give α-deoxyglycosides in high yields and with excellent selectivity. The utility of the reaction was demonstrated by the synthesis of oligosaccharides through the coupling reaction followed by deprotection.
#
#