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Neuropediatrics 2016; 47(02): 115-118
DOI: 10.1055/s-0035-1570752
Short Communication
Georg Thieme Verlag KG Stuttgart · New York

Interhemispheric Lipoma, Callosal Anomaly, and Malformations of Cortical Development: A Case Series

Tetsu Niwa
1   Department of Radiology, Tokai University School of Medicine, Shimokasuya, Isehara, Japan
2   Department of Radiology, Kanagawa Children's Medical Center, Mutsukawa, Minami-ku, Yokohama, Japan
,
Linda S. de Vries
3   Department of Perinatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
,
Gwendolyn T. R. Manten
3   Department of Perinatology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
,
Maarten Lequin
4   Department of Paediatric Radiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
,
Inge Cuppen
5   Department of Paediatric Neurology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
,
Jun Shibasaki
6   Department of Neonatology, Kanagawa Children's Medical Center, Mutsukawa, Minami-ku, Yokohama, Japan
,
Noriko Aida
2   Department of Radiology, Kanagawa Children's Medical Center, Mutsukawa, Minami-ku, Yokohama, Japan
› Author Affiliations
Further Information

Publication History

05 August 2015

09 November 2015

Publication Date:
25 January 2016 (online)

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Abstract

Intracranial lipomas are rare congenital malformations. The most common type of intracranial lipoma is the interhemispheric lipoma, which is frequently associated with callosal anomalies such as hypogenesis or agenesis of the corpus callosum. In contrast, interhemispheric lipomas are less often accompanied with malformations of cortical development (MCD). We report magnetic resonance imaging findings of three infants with an interhemispheric lipoma, associated with a callosal anomaly, and MCD: two infants with nodular interhemispheric lipoma, agenesis of the corpus callosum, and polymicrogyria, and one infant with interhemispheric curvilinear lipoma, hypoplasia of the corpus callosum, and heterotopias. An association was suggested regarding the occurrence of these malformations.

Keywords

interhemispheric lipoma - callosal anomaly - malformations of cortical development - magnetic resonance imaging - infant

Supplementary Material

 

  • References

  • 1 Jabot G, Stoquart-Elsankari S, Saliou G, Toussaint P, Deramond H, Lehmann P. Intracranial lipomas: clinical appearances on neuroimaging and clinical significance. J Neurol 2009; 256 (6) 851-855
    CrossrefPubMedSearch in Google Scholar
  • 2 Kakita A, Inenaga C, Kameyama S , et al. Cerebral lipoma and the underlying cortex of the temporal lobe: pathological features associated with the malformation. Acta Neuropathol 2005; 109 (3) 339-345
    CrossrefPubMedSearch in Google Scholar
  • 3 Yilmaz N, Unal O, Kiymaz N, Yilmaz C, Etlik O. Intracranial lipomas—a clinical study. Clin Neurol Neurosurg 2006; 108 (4) 363-368
    CrossrefPubMedSearch in Google Scholar
  • 4 Nunes JC, Martins RF, Bastos A , et al. Brain lipoma, corpus callosum hypoplasia and polymicrogyria in familial multiple lipomatosis. Clin Neurol Neurosurg 2013; 115 (7) 1157-1159
    CrossrefPubMedSearch in Google Scholar
  • 5 Yildiz H, Hakyemez B, Koroglu M, Yesildag A, Baykal B. Intracranial lipomas: importance of localization. Neuroradiology 2006; 48 (1) 1-7
    PubMedSearch in Google Scholar
  • 6 Thakur S, Sood RG, Jhobta A, Makhaik S, Thakur C. Sylvian fissure lipoma with angiomatous component and associated brain malformation: a case report. Iran J Neurol 2013; 12 (4) 169-171
    PubMedSearch in Google Scholar
  • 7 Saatci I, Aslan C, Renda Y, Besim A. Parietal lipoma associated with cortical dysplasia and abnormal vasculature: case report and review of the literature. AJNR Am J Neuroradiol 2000; 21 (9) 1718-1721
    PubMedSearch in Google Scholar
  • 8 Barkovich J, Raybaud C. Intracranial lipomas. In: Barkovich AJ, Raybaud C, eds. Pediatric Neuroimaging. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2011: 520-524
    Search in Google Scholar
  • 9 Elmakky A, Carli D, Lugli L , et al. A three-generation family with terminal microdeletion involving 5p15.33-32 due to a whole-arm 5;15 chromosomal translocation with a steady phenotype of atypical cri du chat syndrome. Eur J Med Genet 2014; 57 (4) 145-150
    CrossrefPubMedSearch in Google Scholar
  • 10 Utsunomiya H, Ogasawara T, Hayashi T, Hashimoto T, Okazaki M. Dysgenesis of the corpus callosum and associated telencephalic anomalies: MRI. Neuroradiology 1997; 39 (4) 302-310
    CrossrefPubMedSearch in Google Scholar
  • 11 Sommet J, Schiff M, Evrard P, Blanc R, Elmaleh-Bergès M. Pericallosal lipoma and middle cerebral artery aneurysm: a coincidence?. Pediatr Radiol 2010; 40 (8) 1417-1420
    CrossrefPubMedSearch in Google Scholar