J Reconstr Microsurg 2015; 31(08): 558-564
DOI: 10.1055/s-0035-1555139
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Early Postoperative Complications following Gracilis Free Muscle Transfer for Facial Reanimation: A Systematic Review and Pooled Data Analysis

Ryan M. Garcia
1   Division of Plastic, Reconstructive, Oral, Maxillofacial Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina
,
Arun K. Gosain
2   Department of Plastic and Reconstructive Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois
,
Michael R. Zenn
1   Division of Plastic, Reconstructive, Oral, Maxillofacial Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina
,
Jeffrey R. Marcus
1   Division of Plastic, Reconstructive, Oral, Maxillofacial Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina
› Author Affiliations
Further Information

Publication History

29 December 2014

25 April 2015

Publication Date:
28 July 2015 (online)

Abstract

Background Multiple studies have detailed promising smile restoration following gracilis free muscle transfer for facial reanimation but information detailing the potential complications is lacking. The aim of this study is to systematically review the literature to evaluate the reported complication rate associated with this procedure. We also aim to determine the most common occurring complications.

Methods The PubMed, Embase, and Web of Science databases were queried with multiple search strategies for published articles between January 1950 and February 2013 that detailed gracilis free muscle transfer for facial reanimation. Title, abstract, and full text review was performed. Complications were defined as any reported, identifiable adverse outcome that required an alteration in treatment for correction.

Results The literature search yielded 62 studies of gracilis free muscle transfer for facial reanimation. Overall, 36 articles (58%) reported whether or not a complication had occurred. The overall complication rate based on pooled proportions was 9.6% and the most commonly occurring complications were postoperative hematoma (3.6%) and infection (3.5%).

Conclusions Our data suggests that complications after gracilis free muscle transfer for facial reanimation may be underreported and this complex procedure may in fact be associated with significant adverse outcomes as high as 9.6%.

 
  • References

  • 1 Ylä-Kotola TM, Kauhanen MS, Asko-Seljavaara SL. Facial reanimation by transplantation of a microneurovascular muscle: long-term follow-up. Scand J Plast Reconstr Surg Hand Surg 2004; 38 (5) 272-276
  • 2 O'Brien BM, Pederson WC, Khazanchi RK, Morrison WA, MacLeod AM, Kumar V. Results of management of facial palsy with microvascular free-muscle transfer. Plast Reconstr Surg 1990; 86 (1) 12-22 , discussion 23–24
  • 3 Terzis JK, Noah ME. Analysis of 100 cases of free-muscle transplantation for facial paralysis. Plast Reconstr Surg 1997; 99 (7) 1905-1921
  • 4 Manktelow RT, Tomat LR, Zuker RM, Chang M. Smile reconstruction in adults with free muscle transfer innervated by the masseter motor nerve: effectiveness and cerebral adaptation. Plast Reconstr Surg 2006; 118 (4) 885-899
  • 5 Kumar PA. Cross-face reanimation of the paralysed face, with a single stage microneurovascular gracilis transfer without nerve graft: a preliminary report. Br J Plast Surg 1995; 48 (2) 83-88
  • 6 Faria JC, Scopel GP, Busnardo FF, Ferreira MC. Nerve sources for facial reanimation with muscle transplant in patients with unilateral facial palsy: clinical analysis of 3 techniques. Ann Plast Surg 2007; 59 (1) 87-91
  • 7 Chuang DC. Free tissue transfer for the treatment of facial paralysis. Facial Plast Surg 2008; 24 (2) 194-203
  • 8 Bianchi B, Copelli C, Ferrari S, Ferri A, Bailleul C, Sesenna E. Facial animation with free-muscle transfer innervated by the masseter motor nerve in unilateral facial paralysis. J Oral Maxillofac Surg 2010; 68 (7) 1524-1529
  • 9 Horta R, Silva P, Silva A , et al. Facial reanimation with gracilis muscle transplantation and obturator nerve coaptation to the motor nerve of masseter muscle as a salvage procedure in an unreliable cross-face nerve graft. Microsurgery 2011; 31 (2) 164-166
  • 10 Terzis JK, Konofaos P. Novel use of C7 spinal nerve for Moebius. Plast Reconstr Surg 2010; 126 (1) 106-117
  • 11 Cardenas-Mejia A, Covarrubias-Ramirez JV, Bello-Margolis A, Rozen S. Double innervated free functional muscle transfer for facial reanimation. J Plast Surg Hand Surg 2015; 49 (3) 183-188
  • 12 Snyder-Warwick AK, Fattah AY, Zive L, Halliday W, Borschel GH, Zuker RM. The degree of facial movement following microvascular muscle transfer in pediatric facial reanimation depends on donor motor nerve axonal density. Plast Reconstr Surg 2015; 135 (2) 370e-381e
  • 13 Lee LN, Susarla SM, Henstrom DK , et al. Surgical site infections after gracilis free flap reconstruction for facial paralysis. Otolaryngol Head Neck Surg 2012; 147 (2) 245-248
  • 14 Lee LN, Henstrom D, Cheney M, Durand M, Hadlock T. Infections after gracilis free flap reconstruction. Otolaryngol Head Neck Surg 2011; 145 (2) 47-48
  • 15 Stroup DF, Berlin JA, Morton SC , et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 2000; 283 (15) 2008-2012
  • 16 Bianchi B, Copelli C, Ferrari S, Ferri A, Sesenna E. Facial animation in patients with Moebius and Moebius-like syndromes. Int J Oral Maxillofac Surg 2010; 39 (11) 1066-1073
  • 17 Eisenhardt SU, Eisenhardt NA, Thiele JR, Stark GB, Bannasch H. Salvage procedures after failed facial reanimation surgery using the masseteric nerve as the motor nerve for free functional gracilis muscle transfer. JAMA Facial Plast Surg 2014; 16 (5) 359-363
  • 18 Hontanilla B, Marre D, Cabello A. Facial reanimation with gracilis muscle transfer neurotized to cross-facial nerve graft versus masseteric nerve: a comparative study using the FACIAL CLIMA evaluating system. Plast Reconstr Surg 2013; 131 (6) 1241-1252
  • 19 Win TS, Tzafetta K. Power and coordination for facial reanimation - dual innervation of free gracilis transfer using masseteric nerve and cross-facial nerve graft. Plast Reconstr Surg 2014; 134 (4) (Suppl. 01) 13
  • 20 Terzis JK, Olivares FS. Use of mini-temporalis transposition to improve free muscle outcomes for smile. Plast Reconstr Surg 2008; 122 (6) 1723-1732
  • 21 Bianchi B, Copelli C, Ferrari S, Ferri A, Sesenna E. Facial animation in children with Moebius and Moebius-like syndromes. J Pediatr Surg 2009; 44 (11) 2236-2242
  • 22 Bianchi B, Copelli C, Ferrari S, Ferri A, Sesenna E. Successful salvage surgery after treatment failures with cross graft and free muscle transplant in facial reanimation. J Craniomaxillofac Surg 2012; 40 (2) 185-189
  • 23 Bianchi B, Copelli C, Ferrari S, Ferri A, Sesenna E. Use of the masseter motor nerve in facial animation with free muscle transfer. Br J Oral Maxillofac Surg 2012; 50 (7) 650-653
  • 24 Chuang DC, Mardini S, Lin SH, Chen HC. Free proximal gracilis muscle and its skin paddle compound flap transplantation for complex facial paralysis. Plast Reconstr Surg 2004; 113 (1) 126-132 , discussion 133–135
  • 25 Faria JC, Scopel GP, Alonso N, Ferreira MC. Muscle transplants for facial reanimation: rationale and results of insertion technique using the palmaris longus tendon. Ann Plast Surg 2009; 63 (2) 148-152
  • 26 Fatemi MJ, Forootan SK, Habibi M, Pooli AH, Mansoori MJ. Toward shortening interoperation period in two-stage cross facial nerve graft with muscle transfer. Ann Plast Surg 2008; 60 (6) 639-643
  • 27 Gousheh J, Arasteh E. Treatment of facial paralysis: dynamic reanimation of spontaneous facial expression-apropos of 655 patients. Plast Reconstr Surg 2011; 128 (6) 693e-703e
  • 28 Hadlock TA, Malo JS, Cheney ML, Henstrom DK. Free gracilis transfer for smile in children: the Massachusetts Eye and Ear Infirmary Experience in excursion and quality-of-life changes. Arch Facial Plast Surg 2011; 13 (3) 190-194
  • 29 Hontanilla B, Aubá C. Smile reconstruction through bilateral muscular transplants neurotized by hypoglossal nerves. J Craniofac Surg 2011; 22 (3) 845-847
  • 30 Hontanilla B, Rodriguez-Losada G. Bilateral reconstruction of smile through muscular transplants neurotized to masseter nerves. J Craniofac Surg 2011; 22 (3) 1099-1100
  • 31 Krishnan KG, Schackert G, Seifert V. Outcomes of microneurovascular facial reanimation using masseteric innervation in patients with long-standing facial palsy resulting from cured brainstem lesions. Neurosurgery 2010; 67 (3) 663-674 , discussion 674
  • 32 Kumar PA, Hassan KM. Cross-face nerve graft with free-muscle transfer for reanimation of the paralyzed face: a comparative study of the single-stage and two-stage procedures. Plast Reconstr Surg 2002; 109 (2) 451-462 , discussion 463–464
  • 33 Lu JC, Chuang DC. One-stage reconstruction for bilateral Möbius syndrome: simultaneous use of bilateral spinal accessory nerves to innervate 2 free muscles for facial reanimation. Ann Plast Surg 2013; 70 (2) 180-186
  • 34 Lykoudis EG, Spyropoulou GA, Vlastou CC. The conjoint medial circumflex femoral perforator and gracilis muscle free flap: anatomical study and clinical use for complex facial paralysis reconstruction. Plast Reconstr Surg 2005; 116 (6) 1589-1595
  • 35 Marre D, Hontanilla B. Brain plasticity in Möbius syndrome after unilateral muscle transfer: case report and review of the literature. Ann Plast Surg 2012; 68 (1) 97-100
  • 36 Richard BM. Location of the extracranial extent of leprous facial nerve pathology may allow leprous facial palsy to be reanimated by free muscle transfer. Br J Plast Surg 2003; 56 (1) 14-19 , discussion 20
  • 37 Sassoon EM, Poole MD, Rushworth G. Reanimation for facial palsy using gracilis muscle grafts. Br J Plast Surg 1991; 44 (3) 195-200
  • 38 Schliephake H, Schmelzeisen R, Tröger M. Revascularized muscle transfer for facial reanimation after long-standing facial paralysis. Int J Oral Maxillofac Surg 2000; 29 (4) 243-249
  • 39 Shridharani SM, Stapleton SM, Redett RJ, Magarakis M, Rosson GD. Use of gastrointestinal anastomosis stapler for harvest of gracilis muscle and securing it in the face for facial reanimation: a novel technique. Eplasty 2010; 10: e29
  • 40 Takushima A, Harii K, Asato H, Yamada A. Neurovascular free-muscle transfer to treat facial paralysis associated with hemifacial microsomia. Plast Reconstr Surg 2002; 109 (4) 1219-1227
  • 41 Vakharia KT, Henstrom D, Plotkin SR, Cheney M, Hadlock T. Facial reanimation of patients with neurofibromatosis type 2. Neurosurgery 2012; 70 (2, Suppl Operative): 237-243
  • 42 Vakharia KT, Henstrom D, Lindsay R, Cunnane MB, Cheney M, Hadlock T. Color Doppler ultrasound: effective monitoring of the buried free flap in facial reanimation. Otolaryngol Head Neck Surg 2012; 146 (3) 372-376
  • 43 Ylä-Kotola TM, Kauhanen MS, Koskinen SK, Asko-Seljavaara SL. Magnetic resonance imaging of microneurovascular free muscle flaps in facial reanimation. Br J Plast Surg 2005; 58 (1) 22-27
  • 44 Zuker RM, Goldberg CS, Manktelow RT. Facial animation in children with Möbius syndrome after segmental gracilis muscle transplant. Plast Reconstr Surg 2000; 106 (1) 1-8 , discussion 9