Abstract
Previous studies have demonstrated gender-related differences in early and late outcomes
following type A dissection diagnosis. However, it is widely unknown whether gender
affects early clinical outcomes and survival after repair of type A aortic dissection.
The goal of this study was to compare the early and late clinical outcomes in women
versus men after repair of acute type A aortic dissections.
Between January 2000 and October 2010 a total of 251 patients from four academic medical
centers underwent repair of acute type A aortic dissection. Of those, 79 were women
and 172 were men with median ages of 67 (range, 20–87 years) and 58 years (range,
19–83 years), respectively (p < 0.001). Major morbidity, operative mortality, and 10-year actuarial survival were
compared between the groups.
Operative mortality was not significantly influenced by gender (19% for women vs.
17% for men, p = 0.695). There were similar rates of hemodynamic instability (12% for women vs.
13% men, p = 0.783) between the two groups. Actuarial 10-year survival rates were 58% for women
versus 73% for men (p = 0.284).
Gender does not significantly impact early clinical outcomes and actuarial survival
following repair of acute type A aortic dissection.
Keywords
aortic dissection - repair - dissection - cardiac surgery