Effect of Quercetin-3-O-Sambubioside Isolated from Eucommia ulmoides Male Flowers on Spontaneous Activity and Convulsion Rate in Mice

Abstract

The purpose of this study was to evaluate the effects of quercetin-3-O-sambubioside on the neural system. Quercetin-3-O-sambubioside is a monomeric compound found in Eucommia ulmoides male flowers from which it was extracted using a system solvent method. In the experiments, spontaneous activity and convulsion rate in mice were recorded, and quercetin-3-O-sambubioside shows eminent effects similar to nikethamide on increasing spontaneous activity and stimulating the nerve center to enhance excitement. These findings are indicative of the powerful ability of quercetin-3-O-sambubioside to promote the stimulation of the nerve center.

Key words

Eucommia ulmoides - Eucommiaceae - quercetin-3-O-sambubioside - neural excitation - excitement

• References

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