Genitaler Lichen sclerosus – Diagnostik und Therapie

Kernaussagen

Der Lichen sclerosus ist eine oft verkannte Erkrankung mit dem potenziellen Risiko einer malignen Entartung. Deshalb ist eine genaue Diagnostik zur Vermeidung der Diagnoseverschleppung notwendig. Bei Verdacht auf Dysplasie oder Malignität sollte immer eine Biopsie erfolgen.

Die Standardtherapie erfolgt mit topischen Glukokortikoiden. Sollten diese nicht den gewünschten Erfolg bringen, kann ein Therapieversuch mit topischen Calcineurin-Inhibitoren erfolgen. Begleitend sollten rückfettende Salben verwendet werden.

Chirurgische Verfahren sind lediglich bei sehr gut selektiertem und symptomatischem Patientenkollektiv oder bei Nachweis einer Dysplasie oder eines Karzinoms durchzuführen.

• Literatur

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