Abstract
Antiphospholipid antibodies (aPL) are associated with a wide range of neurological,
psychological, and psychiatric manifestations. In addition to clearly delineated purely
thrombotic manifestations, which define the neurological contribution to the antiphospholipid
syndrome, the strength of the other described associations is highly variable, and
the underlying pathophysiological mechanisms are not fully understood. Some indications
seem to support a psychiatric impact of aPL. The magnitude of the association and
cellular and molecular mechanisms involved need to be further elucidated.
Keywords
antiphospholipid antibodies - neurology - psychiatry