J Neurol Surg B Skull Base 2014; 75(03): 152-158
DOI: 10.1055/s-0033-1354747
Original Article
Georg Thieme Verlag KG Stuttgart · New York

A Review of Stereotactic Radiosurgery Practice in the Management of Skull Base Meningiomas

Elena Vera
1   Department of Anesthesiology, University of Texas Medical Center, Houston, Texas, United States
,
J. Bryan Iorgulescu
2   Department of Neurological Surgery, Weill Cornell Medical College, New York, New York, United States
,
Daniel M.S. Raper
3   Department of Neurosurgery, University of Virginia, Charlottesville, Virginia, United States
,
Karthik Madhavan
4   Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, United States
,
Brian E. Lally
5   Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, Florida, United States
,
Jacques Morcos
4   Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, United States
,
Samy Elhammady
4   Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, United States
,
Jonathan Sherman
6   Department of Neurosurgery, George Washington University School of Medicine, Washington, District of Columbia, United States
,
Ricardo J. Komotar
4   Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, United States
› Author Affiliations
Further Information

Publication History

14 May 2013

01 July 2013

Publication Date:
12 March 2014 (online)

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Abstract

Gross total resection of skull base meningiomas poses a surgical challenge due to their proximity to neurovascular structures. Once the gold standard therapy for skull base meningiomas, microsurgery has been gradually replaced by or used in combination with stereotactic radiosurgery (SRS). This review surveys the safety and efficacy of SRS in the treatment of cranial base meningiomas including 36 articles from 1991 to 2010. SRS produces excellent tumor control with low morbidity rates compared with surgery alone for asymptomatic small skull base meningiomas, patients with risk factors precluding conventional surgery, and as adjuvant therapy for recurrent or residual lesions.