Maligne Lymphome im Larynx

Zusammenfassung

Maligne hämatologische Erkrankungen, wie das hochmaligne diffuse großzellige B-Zell Non ­Hodgkin Lymphom, das MALT Lymphom und das extramedulläre Plasmozytom manifestieren sich äußerst selten lokal im Larynx. In dieser Arbeit werden klinische Symptome, laryngoskopische Befunde, Diagnostik sowie Therapiekonzepte dieser Tumore zusammengefasst. Da klassisch pathognomonische Befunde fehlen, wird die Diagnosestellung erschwert und verzögert. Deshalb muss bei suspekten Larynxveränderungen zwingend eine bioptische Sicherung durchgeführt werden, um gegebenenfalls auch eine Lymphommanifestation auszuschließen.

Abstract

Malignant Lymphoma in the Larynx

Malignant haematological diseases such as the highly malignant diffuse large B-cell lymphoma, the MALT-lymphoma and the extramedullary plasmocytoma are seldom located in the larynx. In this review, clinical symptoms, laryngoscopic findings, further diagnostics as well as therapy concepts are presented. Diagnosis is complicated and delayed due to the absence of classical pathognomic findings. Biopsy of the affected tissue can secure a correct diagnosis and malignant haematological disease can be ruled out.

Schlüsselwörter

Larynx - Lymphome - Symptome - laryngoskopische Befunde - Diagnostik

Key words

larynx - lymphoma - symptoms - laryngoscopic findings - diagnosis

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