Thorac Cardiovasc Surg 2013; 61(06): 530-536
DOI: 10.1055/s-0032-1322545
Original Cardiovascular
Georg Thieme Verlag KG Stuttgart · New York

A 30-Year-Single-Center Experience in Atrial Myxomas: From Presentation to Treatment and Prognosis

Biljana Obrenović-Kirćanski
1   Faculty of Medicine, Division of Cardiology, Clinical Center of Serbia, University of Belgrade, Belgrade, Serbia
,
Aleksandar Mikić
2   Faculty of Medicine, Division of Cardiac Surgery, Clinical Center of Serbia, University of Belgrade, Belgrade, Serbia
,
Biljana Parapid
1   Faculty of Medicine, Division of Cardiology, Clinical Center of Serbia, University of Belgrade, Belgrade, Serbia
,
Petar Djukić
2   Faculty of Medicine, Division of Cardiac Surgery, Clinical Center of Serbia, University of Belgrade, Belgrade, Serbia
,
Vladimir Kanjuh
1   Faculty of Medicine, Division of Cardiology, Clinical Center of Serbia, University of Belgrade, Belgrade, Serbia
,
Nataša Milić
1   Faculty of Medicine, Division of Cardiology, Clinical Center of Serbia, University of Belgrade, Belgrade, Serbia
,
Nataša Kovačević-Kostić
2   Faculty of Medicine, Division of Cardiac Surgery, Clinical Center of Serbia, University of Belgrade, Belgrade, Serbia
,
Miloš Velinović
2   Faculty of Medicine, Division of Cardiac Surgery, Clinical Center of Serbia, University of Belgrade, Belgrade, Serbia
,
Petar Seferović
1   Faculty of Medicine, Division of Cardiology, Clinical Center of Serbia, University of Belgrade, Belgrade, Serbia
,
Mile Vraneš
2   Faculty of Medicine, Division of Cardiac Surgery, Clinical Center of Serbia, University of Belgrade, Belgrade, Serbia
› Author Affiliations
Further Information

Publication History

27 February 2012

18 May 2012

Publication Date:
03 August 2012 (online)

Abstract

Background The symptoms of myxoma are atypical, vary greatly, and may mimic numerous conditions. Our aim was to investigate the correlation of localization, size, and consistency of myxoma with its treatment and prognosis.

Methods Over a span of 30 years, 74 consecutive patients (24 men, mean age 46.7 years) were surgically treated for echocardiography-diagnosed myxomas at our center.

Results Left atrial myxomas were more frequent (89.19%), with the racemous form being predominantly left-sided and having no difference in tumor size regardless of localization. Three patients were asymptomatic; and those who were symptomatic, symptoms appeared 2 to 36 months (mean 13.60 ± 7.52) before diagnosis. Nonspecific symptoms and signs were present in 91.98% of patients, whereas specific symptoms and signs were present in 74.32%. More often, patients with myxomas >5 cm in diameter were symptomatic. Embolic events occurred in 15 patients (9 cerebral, 4 pulmonary, 2 peripheral), more frequently in right atrial myxomas of >5 cm diameter. All patients were surgically treated on diagnoses, with no intraoperative mortality or recurrences.

Conclusions Symptoms in our cardiac myxoma patients were more pronounced when the myxomas were left-sided, racemous, and over 5 cm in diameter. Even in asymptomatic patients, a high index of suspicion assured timely diagnosis and management.

 
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