J Neurol Surg B Skull Base 2012; 73(03): 190-196
DOI: 10.1055/s-0032-1312706
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Endoscopic Endonasal Management of Recurrent Petrous Apex Cholesterol Granuloma

Nancy McLaughlin
1   Brain Tumor Center, John Wayne Cancer Institute of Saint John's Health Center, Santa Monica, California, United States
,
Daniel F. Kelly
1   Brain Tumor Center, John Wayne Cancer Institute of Saint John's Health Center, Santa Monica, California, United States
,
Daniel M. Prevedello
1   Brain Tumor Center, John Wayne Cancer Institute of Saint John's Health Center, Santa Monica, California, United States
,
Kiarash Shahlaie
1   Brain Tumor Center, John Wayne Cancer Institute of Saint John's Health Center, Santa Monica, California, United States
,
Ricardo L. Carrau
3   Department of Head and Neck Surgery, The Ohio State University, Columbus, Ohio, United States
,
Amin B. Kassam
4   Department of Surgery, Division of Neurosurgery, University of Ottawa, Ontario, Canada
› Author Affiliations
Further Information

Publication History

07 August 2010

15 November 2010

Publication Date:
17 May 2012 (online)

Preview

Abstract

Introduction Petrous apex cholesterol granulomas (PACGs) are uncommon lesions. Recurrence following transcranial or endonasal approaches to aerate the cyst occurs in up to 60% of cases. We describe the technical nuances pertinent to the endonasal endoscopic management of a recurrent symptomatic PACG and review the literature.

Results A 19-year-old woman presented with a recurrent abducens nerve paresis. Four months prior, she underwent an endonasal transsphenoidal surgery (TSS) for drainage of a symptomatic PACG. Current imaging documented recurrence of the right PACG. Transsphenoidal and infrapetrous approaches were performed to obtain a wider bony opening along the petrous apex and drain the cyst. A Doyle splint was inserted into the cyst's cavity and extended out into the sphenoid sinus, maintaining patency during the healing process. Three months after surgery, the splint was removed endoscopically, allowing visualization of a patent cylindrical communication between both aerated cavities. The patient remains symptom-free and recurrence-free.

Conclusion Endoscopic endonasal surgery must be adapted to manage a recurrent PACG. A TSS may not be sufficient. An infrapetrous approach with wider bony opening, extensive removal of the cyst's anterior wall, and the use of a stent are indicated for the treatment of recurrent PACG and to prevent recurrences.