Cent Eur Neurosurg 2012; 73(02): 103-105
DOI: 10.1055/s-0032-1309068
Case Report
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Fluorescence-Guided Resection of Spinal Metastases of Malignant Glioma: Report of 2 Cases[*]

M. Rapp
1   Heinrich Heine Medical Centre, Neurosurgery, Duesseldorf, Germany
,
M. Klingenhöfer
2   Westfaelische Wilhelms-University, Neurosurgery, Muenster, Germany
,
J. Felsberg
3   Heinrich Heine Medical Centre, Neuropathology, Duesseldorf, Germany
,
H. J. Steiger
1   Heinrich Heine Medical Centre, Neurosurgery, Duesseldorf, Germany
,
W. Stummer
2   Westfaelische Wilhelms-University, Neurosurgery, Muenster, Germany
,
M. Sabel
1   Heinrich Heine Medical Centre, Neurosurgery, Duesseldorf, Germany
› Author Affiliations
Further Information

Publication History

Publication Date:
30 March 2012 (online)

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Introduction

Malignant gliomas rarely metastasize outside the central nervous system.[4] Therefore, data on surgical resection and its impact on the outcome for metastatic manifestations of these entities are limited. Since the pivotal publication of Stummer et al., 5-ALA-based fluorescence-guided surgery (FGS) is well established for the resection of cerebral malignant gliomas.[3] [5] [6] [7] [8] [9] To date, there are no reports investigating the potential role of FGS for extracranial manifestations of this disease. Therefore, we report our experience with FGS for spinal epidural, intradural, and intraosseous metastases of a World Health Organization (WHO) grade IV glioblastoma and a WHO grade III anaplastic oligodendroglioma in the lumbar and thoracic spine, respectively.

* This article was originally Published online in Central European Neurosurgery on March 10, 2011 (DOI:10.1055/s-0030-1268499)