ABSTRACT
Pulmonary embolism (PE) has long been described in children. Nevertheless, most of
the algorithms applied to patients within this age range, from diagnosis to therapy,
have been adapted from adult protocols. This article reviews the progresses that occurred
to PE in children placing them in historical perspective with the key events relevant
to PE in adults. A brief summary of the initial reports encountered in the pediatric
literature followed by key conclusions drawn from national database reports characterizing
its epidemiology in children is highlighted. Additionally, a section with the diagnostic
tools pertaining to children is included. Closing remarks encompass commentaries related
to therapy and outcomes, reflecting on current knowledge gaps related to PE in children.
KEYWORDS
Anticoagulation - children - deep vein thrombosis - pulmonary embolism - pulmonary
hypertension
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Leonardo R. BrandãoM.D.
The Hospital for Sick Children
555 University Avenue, Black Wing, Room 10412, Toronto, ON M5G 1X8, Canada
Email: leonardo.brandao@sickkids.ca
