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Semin Thromb Hemost 2011; 37(7): 772-785
DOI: 10.1055/s-0031-1297168
© Thieme Medical Publishers

Pulmonary Embolism in Children

Leonardo R. Brandão1 , Veerle Labarque1 , Yaser Diab1 , Suzan Williams1 , David E. Manson2
  • 1Department of Paediatrics, Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
  • 2Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada
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Publication History

Publication Date:
20 December 2011 (online)

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ABSTRACT

Pulmonary embolism (PE) has long been described in children. Nevertheless, most of the algorithms applied to patients within this age range, from diagnosis to therapy, have been adapted from adult protocols. This article reviews the progresses that occurred to PE in children placing them in historical perspective with the key events relevant to PE in adults. A brief summary of the initial reports encountered in the pediatric literature followed by key conclusions drawn from national database reports characterizing its epidemiology in children is highlighted. Additionally, a section with the diagnostic tools pertaining to children is included. Closing remarks encompass commentaries related to therapy and outcomes, reflecting on current knowledge gaps related to PE in children.

KEYWORDS

Anticoagulation - children - deep vein thrombosis - pulmonary embolism - pulmonary hypertension

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Leonardo R. BrandãoM.D. 

The Hospital for Sick Children

555 University Avenue, Black Wing, Room 10412, Toronto, ON M5G 1X8, Canada

Email: leonardo.brandao@sickkids.ca