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DOI: 10.1055/s-0031-1296088
© Thieme Medical Publishers
Liver Abscess Following Transarterial Chemoembolization
Publication History
Publication Date:
03 January 2012 (online)

Transarterial chemoembolization (TACE) alone or in combination with thermoablation is commonly used in treating primary and secondary liver malignancies.[1] [2] It has proven to be safe and effective in treating hepatocellular carcinoma (HCC), neuroendocrine tumors, ocular melanoma, cholangiocarcinoma, and sarcoma. Known complications from hepatic embolization include the self-limiting postembolization syndrome (i.e., pain, nausea, vomiting, fever), liver infarction, liver failure, liver abscess, biloma formation, gastrointestinal bleeding, tumor rupture, septicemia, and pulmonary embolism. Approximately 5% of patients will have serious adverse events after chemoembolization, with the most common being liver abscess or liver infarction.[1] This case reviews the incidence, risk factors, diagnosis, and treatment of liver abscess following chemoembolization as well as prophylactic measures to prevent its occurrence.
REFERENCES
- 1
Brown D B, Geschwind J F, Soulen M C, Millward S F, Sacks D.
Society of Interventional Radiology Position Statement on Chemoembolization of Hepatic
Malignancies.
J Vasc Interv Radiol.
2006;
17
(2 Pt 1)
217-223
MissingFormLabel
- 2
Maluccio M, Covey A M, Gandhi R et al..
Comparison of survival rates after bland arterial embolization and ablation versus
surgical resection for treating solitary hepatocellular carcinoma up to 7 cm.
J Vasc Interv Radiol.
2005;
16
(7)
955-961
MissingFormLabel
- 3
Mezhir J J, Fong Y, Fleischer D et al..
Pyogenic abscess after hepatic artery embolization: a rare but potentially lethal
complication.
J Vasc Interv Radiol.
2011;
22
(2)
177-182
MissingFormLabel
- 4
Sakamoto I, Aso N, Nagaoki K et al..
Complications associated with transcatheter arterial embolization for hepatic tumors.
Radiographics.
1998;
18
(3)
605-619
MissingFormLabel
- 5
Song S Y, Chung J W, Han J K et al..
Liver abscess after transcatheter oily chemoembolization for hepatic tumors: incidence,
predisposing factors, and clinical outcome.
J Vasc Interv Radiol.
2001;
12
(3)
313-320
MissingFormLabel
- 6
Ong G Y, Changchien C S, Lee C M et al..
Liver abscess complicating transcatheter arterial embolization: a rare but serious
complication. A retrospective study after 3878 procedures.
Eur J Gastroenterol Hepatol.
2004;
16
(8)
737-742
MissingFormLabel
- 7
de Baère T, Roche A, Amenabar J M et al..
Liver abscess formation after local treatment of liver tumors.
Hepatology.
1996;
23
(6)
1436-1440
MissingFormLabel
- 8
Kim W, Clark T W, Baum R A, Soulen M C.
Risk factors for liver abscess formation after hepatic chemoembolization.
J Vasc Interv Radiol.
2001;
12
(8)
965-968
MissingFormLabel
- 9
Chen C, Chen P J, Yang P M et al..
Clinical and microbiological features of liver abscess after transarterial embolization
for hepatocellular carcinoma.
Am J Gastroenterol.
1997;
92
(12)
2257-2259
MissingFormLabel
- 10
Mezhir J J, Fong Y, Jacks L M et al..
Current management of pyogenic liver abscess: surgery is now second-line treatment.
J Am Coll Surg.
2010;
210
(6)
975-983
MissingFormLabel
- 11
Venkatesan A M, Kundu S, Sacks D et al..
Practice guidelines for adult antibiotic prophylaxis during vascular and intervention
radiology procedures.
J Vasc Interv Radiol.
2010;
21
1611-1630
MissingFormLabel
- 12
Geschwind J F, Kaushik S, Ramsey D E, Choti M A, Fishman E K, Kobeiter H.
Influence of a new prophylactic antibiotic therapy on the incidence of liver abscesses
after chemoembolization treatment of liver tumors.
J Vasc Interv Radiol.
2002;
13
(11)
1163-1166
MissingFormLabel
- 13
Patel S, Tuite C M, Mondschein J I, Soulen M C.
Effectiveness of an aggressive antibiotic regimen for chemoembolization in patients
with previous biliary intervention.
J Vasc Interv Radiol.
2006;
17
(12)
1931-1934
MissingFormLabel
Danny ChengM.D.
University of Chicago Medical Center
5840 S. Maryland Ave., MC 2026 Chicago, IL 60637
Email: danny.cheng@uchospitals.edu