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Synfacts 2011(11): 1161-1161  
DOI: 10.1055/s-0031-1289272
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Synechoxanthin

Contributor(s): Steven V. Ley, Catherine F. Carter
S. Fujii, S. Y. Chang, M. D. Burke*
University of Illinois at Urbana-Champaign, USA
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Publication History

Publication Date:
19 October 2011 (online)

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Significance

Synechoxanthin was isolated in 2008 from the cyanobacterium Synechococcus sp. strain PCC 7002. It is being studied for its ­exceptionally strong antioxidant properties. The total synthesis is achieved here using an iterative cross-coupling approach for a rapid and stereocontrolled assembly of the polyene chain.