Use of 1,2,4-Triazolyl-1,2,3-Triazoles as Carbene Precursors

Significance

Diazo compounds are excellent precursors for the generation of reactive metal carbenoid species. The authors demonstrate that triazoles bearing an electron-withdrawing heterocycle at the 1-position can serve as carbene precursors, which can subsequently undergo highly enantioselective cyclopropanation reactions or transannulations with nitriles.